• MKN28(MKN-74)人胃癌高转移细胞(STR鉴定正确)

    价 格:¥1800

    期 货:现货(冻存管发2支)

    保藏中心👷🏽:BTCC

    资源编号👨🏼‍🦱:BTCC-1110

    产地:中国

    套 餐🧑🏽‍🚀:

    T25/复苏细胞 无血清冻存液 专用完全培养基500ml 南美特级胎牛血清500ml

    详细资料说明书下载质检报告(COA)

    Cell line nameMKN28
    SynonymsMKN-28; MKN 28
    AccessionBTCC-1110
    Resource Identification InitiativeTo cite this cell line use: MKN28 (BTCC-1110)
    CommentsProblematic cell line: Contaminated. Shown to be a MKN74 derivative (PubMed=20143388).
    Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
    Part of: COSMIC cell lines project.
    Part of: JFCR39 cancer cell line panel.
    Part of: JFCR45 cancer cell line panel.
    Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00328.
    Population: Japanese.
    Doubling time: 28-32 hours (PubMed=3962675); 30-34 hours (CelloPub=CLPUB00584).
    Microsatellite instability: Stable (MSS) (PubMed=23671654; Sanger).
    Omics: Deep exome analysis.
    Omics: Deep quantitative proteome analysis.
    Omics: DNA methylation analysis.
    Omics: SNP array analysis.
    Omics: Transcriptome analysis by microarray.
    Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
    Sequence variations
    HLA typingSource: PubMed=9023415
    Class I
    HLA-AA*31:01
    HLA-BB*51:01
    HLA-CC*03:04

    Source: PubMed=25960936
    Class I
    HLA-BB*51:01
    HLA-CC*03:04,03:04
    Class II
    HLA-DRDRB1*15:01,15:01
    Genome ancestrySource: PubMed=30894373

    Origin% genome


    African0
    Native American0
    East Asian, North83.28
    East Asian, South16.71
    South Asian0
    European, North0
    European, South0
    DiseaseGastric tubular adenocarcinoma (NCIt: C5473)
    Species of originHomo sapiens (Human) (NCBI Taxonomy: 9606)
    HierarchyParent: CVCL_2791 (MKN74)
    Children:


    CVCL_UW56 (MKN28-EGFP)CVCL_QZ55 (RMKN-28)
    Sex of cellMale
    Age at sampling37Y
    CategoryCancer cell line
    STR profileSource(s): Cosmic-CLP; JCRB; KCLB; RCB

    Markers:
    AmelogeninX
    CSF1PO12
    D3S135816
    D5S81811
    D7S8209
    D13S31711
    D16S5399,11
    FGA23
    TH016
    TPOX8,11
    vWA16,20

    Run an STR similarity search on this cell line
    Web pageshttps://cellbank.nibiohn.go.jp/legacy/cellbank/qualitycontrol/identification/summary.htm
    https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx
    Publications

    CLPUB00581
    Hojo H.
    Establishment of cultured cell lines of human stomach cancer origin and their morphological characteristics.
    Niigata Igakkai Zasshi 91:737-763(1977)

    CLPUB00584
    Motoya T., Hojo H., Suzuki T., Oboshi S.
    Evaluation of the regrowth assay method as an in vitro drug sensitivity test and its application to cultured human gastric cancer cell lines.
    Acta Med. Biol. 27:49-63(1979)

    PubMed=758928; DOI=10.1038/bjc.1979.3
    Kinjo M., Oka K., Naito S., Kohga S., Tanaka K., Oboshi S., Hayata Y., Yasumoto K.
    Thromboplastic and fibrinolytic activities of cultured human cancer cell lines.
    Br. J. Cancer 39:15-23(1979)

    PubMed=6862145; DOI=10.20772/cancersci1959.74.2_240
    Naito S., Inoue S., Kinjo M., Tanaka K.
    Thromboplastic and fibrinolytic activities of cultured human gastric cancer cell lines.
    Gann 74:240-247(1983)

    PubMed=3986962; DOI=10.1093/carcin/6.4.549
    Watatani M., Ikenaga M., Hatanaka T., Kinuta M., Takai S.-I., Mori T., Kondo S.
    Analysis of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced DNA damage in tumor cell strains from Japanese patients and demonstration of MNNG hypersensitivity of Mer xenografts in athymic nude mice.
    Carcinogenesis 6:549-553(1985)

    PubMed=3962675; DOI=10.1111/j.1440-1827.1986.tb01461.x
    Motoyama T., Hojo H., Watanabe H.
    Comparison of seven cell lines derived from human gastric carcinomas.
    Acta Pathol. Jpn. 36:65-83(1986)

    PubMed=1933850
    Yamada Y., Yoshida T., Hayashi K., Sekiya T., Yokota J., Hirohashi S., Nakatani K., Nakano H., Sugimura T., Terada M.
    p53 gene mutations in gastric cancer metastases and in gastric cancer cell lines derived from metastases.
    Cancer Res. 51:5800-5805(1991)

    PubMed=1370612; DOI=10.1016/S0006-291X(05)80133-0
    Matozaki T., Sakamoto C., Matsuda K., Suzuki T., Konda Y., Nakano O., Wada K., Uchida T., Nishisaki H., Nagao M., Kasuga M.
    Missense mutations and a deletion of the p53 gene in human gastric cancer.
    Biochem. Biophys. Res. Commun. 182:215-223(1992)

    DOI=10.1016/B978-0-12-333530-2.50014-9
    Sekiguchi M., Suzuki T.
    Gastric tumor cell lines.
    (In) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.287-316; Academic Press; New York (1994)

    PubMed=9023415; DOI=10.1006/cimm.1996.1062
    Seki N., Hoshino T., Kikuchi M., Hayashi A., Itoh K.
    HLA-A locus-restricted and tumor-specific CTLs in tumor-infiltrating lymphocytes of patients with non-small cell lung cancer.
    Cell. Immunol. 175:101-110(1997)

    PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::aid-mc5>3.0.CO;2-D
    Jia L.-Q., Osada M., Ishioka C., Gamo M., Ikawa S., Suzuki T., Shimodaira H., Niitani T., Kudo T., Akiyama M., Kimura N., Matsuo M., Mizusawa H., Tanaka N., Koyama H., Namba M., Kanamaru R., Kuroki T.
    Screening the p53 status of human cell lines using a yeast functional assay.
    Mol. Carcinog. 19:243-253(1997)

    PubMed=11107048; DOI=10.1046/j.1440-1827.2000.01117.x
    Yokozaki H.
    Molecular characteristics of eight gastric cancer cell lines established in Japan.
    Pathol. Int. 50:767-777(2000)

    PubMed=11314020; DOI=10.1038/sj.onc.1204160
    Kataoka H., Miura Y., Joh T., Seno K., Tada T., Tamaoki T., Nakabayashi H., Kawaguchi M., Asai K., Kato T., Itoh M.
    Alpha-fetoprotein producing gastric cancer lacks transcription factor ATBF1.
    Oncogene 20:869-873(2001)

    PubMed=15723654; DOI=10.1111/j.1349-7006.2005.00016.x
    Takada H., Imoto I., Tsuda H., Sonoda I., Ichikura T., Mochizuki H., Okanoue T., Inazawa J.
    Screening of DNA copy-number aberrations in gastric cancer cell lines by array-based comparative genomic hybridization.
    Cancer Sci. 96:100-110(2005)

    PubMed=15767549; DOI=10.1158/1535-7163.MCT-04-0234
    Nakatsu N., Yoshida Y., Yamazaki K., Nakamura T., Dan S., Fukui Y., Yamori T.
    Chemosensitivity profile of cancer cell lines and identification of genes determining chemosensitivity by an integrated bioinformatical approach using cDNA arrays.
    Mol. Cancer Ther. 4:399-412(2005)

    PubMed=15900046; DOI=10.1093/jnci/dji133
    Mashima T., Oh-hara T., Sato S., Mochizuki M., Sugimoto Y., Yamazaki K., Hamada J., Tada M., Moriuchi T., Ishikawa Y., Kato Y., Tomoda H., Yamori T., Tsuruo T.
    p53-defective tumors with a functional apoptosome-mediated pathway: a new therapeutic target.
    J. Natl. Cancer Inst. 97:765-777(2005)

    PubMed=15901131; DOI=10.1016/j.prp.2005.01.002
    Murai Y., Hayashi S., Takahashi H., Tsuneyama K., Takano Y.
    Correlation between DNA alterations and p53 and p16 protein expression in cancer cell lines.
    Pathol. Res. Pract. 201:109-115(2005)

    PubMed=20143388; DOI=10.1002/ijc.25242
    Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
    Check your cultures! A list of cross-contaminated or misidentified cell lines.
    Int. J. Cancer 127:1-8(2010)

    PubMed=20164919; DOI=10.1038/nature08768
    Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B.-Y., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.
    Signatures of mutation and selection in the cancer genome.
    Nature 463:893-898(2010)

    PubMed=22336246; DOI=10.1016/j.bmc.2012.01.017
    Kong D., Yamori T.
    JFCR39, a panel of 39 human cancer cell lines, and its application in the discovery and development of anticancer drugs.
    Bioorg. Med. Chem. 20:1947-1951(2012)

    PubMed=22490663; DOI=10.1016/j.bbrc.2012.03.122
    Saiki Y., Yoshino Y., Fujimura H., Manabe T., Kudo Y., Shimada M., Mano N., Nakano T., Lee Y., Shimizu S., Oba S., Fujiwara S., Shimizu H., Chen N., Nezhad Z.K., Jin G., Fukushige S., Sunamura M., Ishida M., Motoi F., Egawa S., Unno M., Horii A.
    DCK is frequently inactivated in acquired gemcitabine-resistant human cancer cells.
    Biochem. Biophys. Res. Commun. 421:98-104(2012)

    PubMed=23671654; DOI=10.1371/journal.pone.0063056
    Lu Y.-H., Soong T.D., Elemento O.
    A novel approach for characterizing microsatellite instability in cancer cells.
    PLoS ONE 8:E63056-E63056(2013)

    PubMed=25960936; DOI=10.4161/21624011.2014.954893
    Boegel S., Lower M., Bukur T., Sahin U., Castle J.C.
    A catalog of HLA type, HLA expression, and neo-epitope candidates in human cancer cell lines.
    OncoImmunology 3:e954893.1-e954893.12(2014)

    PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
    Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X.-M., Egan R.K., Liu Q.-S., Mironenko T., Mitropoulos X., Richardson L., Wang J.-H., Zhang T.-H., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
    A landscape of pharmacogenomic interactions in cancer.
    Cell 166:740-754(2016)

    PubMed=29717028; DOI=10.1042/BSR20180277
    Zhang Y.-Q., Yu S., Zhang Z.-Z., Zhao G., Xu J.
    Long non-coding RNA AK096174 promotes cell proliferation and invasion in gastric cancer by regulating WDR66 expression.
    Biosci. Rep. 38:BSR20180277.1-BSR20180277.12(2018)

    PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
    Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
    An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
    Cancer Res. 79:1263-1273(2019)

    PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010
    Goncalves E., Poulos R.C., Cai Z.-X., Barthorpe S., Manda S.S., Lucas N., Beck A., Bucio-Noble D., Dausmann M., Hall C., Hecker M., Koh J., Lightfoot H., Mahboob S., Mali I., Morris J., Richardson L., Seneviratne A.J., Shepherd R., Sykes E., Thomas F., Valentini S., Williams S.G., Wu Y.-X., Xavier D., MacKenzie K.L., Hains P.G., Tully B., Robinson P.J., Zhong Q., Garnett M.J., Reddel R.R.
    Pan-cancer proteomic map of 949 human cell lines.
    Cancer Cell 40:835-849.e8(2022)

    Cross-references
    Cell line databases/resourcesCell_Model_Passport; SIDM00260
    CGH-DB; 119-1
    CGH-DB; 9021-4
    Cosmic-CLP; 908139
    DepMap; ACH-002161
    LINCS_LDP; LCL-1922
    Anatomy/cell type resourcesBTO; BTO:0002381
    Biological sample resourcesBioSample; SAMN03151847
    Cell line collections (Providers)JCRB; JCRB0253
    JCRB; NIHS0324 - Discontinued
    JCRB; NIHS0325 - Discontinued
    JCRB; FDSC0011 - Discontinued
    KCLB; 80102
    RCB; RCB1000 - Discontinued
    Chemistry resourcesChEMBL-Cells; CHEMBL3307602
    ChEMBL-Targets; CHEMBL614353
    GDSC; 908139
    PharmacoDB; MKN28_937_2019
    PubChem_Cell_line; CVCL_1416
    Encyclopedic resourcesWikidata; Q54905823
    Experimental variables resourcesEFO; EFO_0002831

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