• MOG-G-UVW人脑星形胶质细胞瘤细胞(STR鉴定正确)

    价 格:¥3000

    期 货:现货(冻存管发2支)

    保藏中心:BTCC

    资源编号:BTCC-1392

    产地🕵🏽:中国

    套 餐:

    T25/复苏细胞 无血清冻存液 专用完全培养基500ml 南美特级胎牛血清500ml

    详细资料说明书下载质检报告(COA)

    Cell line nameMOG-G-UVW
    SynonymsMOG-GUVW; MOGGUVW; GO-G-UVW; G-UVW; UVW; Medical Oncology Glascow-Glioma-UVW
    AccessionBTCC-1392
    Resource Identification InitiativeTo cite this cell line use: MOG-G-UVW (RRID:CVCL_2614)
    CommentsPart of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
    Part of: COSMIC cell lines project.
    Population: Caucasian.
    Microsatellite instability: Stable (MSS) (Sanger).
    Omics: CRISPR phenotypic screen.
    Omics: Deep exome analysis.
    Omics: Deep quantitative proteome analysis.
    Omics: DNA methylation analysis.
    Omics: SNP array analysis.
    Omics: Transcriptome analysis by microarray.
    Derived from site: In situ; Brain; UBERON=UBERON_0000955.
    Sequence variations
    • Mutation; HGNC; 11998; TP53; Simple; p.Arg110Pro (c.329G>C); ClinVar=VCV000233627; Zygosity=Homozygous (Cosmic-CLP; DepMap).
    Genome ancestrySource: PubMed=30894373

    Origin% genome


    African1.89
    Native American0
    East Asian, North2.75
    East Asian, South0
    South Asian0
    European, North58.22
    European, South37.14
    DiseaseAnaplastic astrocytoma (NCIt: C9477)
    Anaplastic astrocytoma (ORDO: Orphanet_251589)
    Species of originHomo sapiens (Human) (NCBI Taxonomy: 9606)
    Sex of cellMale
    Age at samplingAge unspecified
    CategoryCancer cell line
    STR profileSource(s): Cosmic-CLP; PubMed=25877200

    Markers:
    AmelogeninX,Y
    CSF1PO10,11
    D2S133821,24
    D3S135815
    D5S81811,12
    D7S8209,12
    D8S117913,15
    D13S31711
    D16S53913
    D18S5114,15
    D19S43314
    D21S1130,30.2
    FGA23,24
    Penta D9,13
    Penta E5,7
    TH016
    TPOX8,9
    vWA15,17

    Run an STR similarity search on this cell line
    Publications

    PubMed=3254724
    Mackie A.E., Freshney R.I., Akturk F., Hunt G.
    Glucocorticoids and the cell surface of human glioma cells: relationship to cytostasis.
    Br. J. Cancer 58 Suppl. 9:101-107(1988)

    PubMed=7518347
    Merzak A., Koochekpour S., Pilkington G.J.
    CD44 mediates human glioma cell adhesion and invasion in vitro.
    Cancer Res. 54:3988-3992(1994)

    PubMed=7591247; DOI=10.1002/ijc.2910630325
    Koochekpour S., Pilkington G.J., Merzak A.
    Hyaluronic acid/CD44H interaction induces cell detachment and stimulates migration and invasion of human glioma cells in vitro.
    Int. J. Cancer 63:450-454(1995)

    PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
    Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
    A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
    Cancer Res. 70:2158-2164(2010)

    PubMed=25877200; DOI=10.1038/nature14397
    Yu M., Selvaraj S.K., Liang-Chu M.M.Y., Aghajani S., Busse M., Yuan J., Lee G., Peale F.V., Klijn C., Bourgon R., Kaminker J.S., Neve R.M.
    A resource for cell line authentication, annotation and quality control.
    Nature 520:307-311(2015)

    PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
    Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X.-M., Egan R.K., Liu Q.-S., Mironenko T., Mitropoulos X., Richardson L., Wang J.-H., Zhang T.-H., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
    A landscape of pharmacogenomic interactions in cancer.
    Cell 166:740-754(2016)

    PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
    Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
    An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
    Cancer Res. 79:1263-1273(2019)

    PubMed=30971826; DOI=10.1038/s41586-019-1103-9
    Behan F.M., Iorio F., Picco G., Goncalves E., Beaver C.M., Migliardi G., Santos R., Rao Y., Sassi F., Pinnelli M., Ansari R., Harper S., Jackson D.A., McRae R., Pooley R., Wilkinson P., van der Meer D.J., Dow D., Buser-Doepner C.A., Bertotti A., Trusolino L., Stronach E.A., Saez-Rodriguez J., Yusa K., Garnett M.J.
    Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens.
    Nature 568:511-516(2019)

    PubMed=31068700; DOI=10.1038/s41586-019-1186-3
    Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J.G., Gelfand E.T., Bielski C.M., Li H.-X., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y.-L., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
    Next-generation characterization of the Cancer Cell Line Encyclopedia.
    Nature 569:503-508(2019)

    PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010
    Goncalves E., Poulos R.C., Cai Z.-X., Barthorpe S., Manda S.S., Lucas N., Beck A., Bucio-Noble D., Dausmann M., Hall C., Hecker M., Koh J., Lightfoot H., Mahboob S., Mali I., Morris J., Richardson L., Seneviratne A.J., Shepherd R., Sykes E., Thomas F., Valentini S., Williams S.G., Wu Y.-X., Xavier D., MacKenzie K.L., Hains P.G., Tully B., Robinson P.J., Zhong Q., Garnett M.J., Reddel R.R.
    Pan-cancer proteomic map of 949 human cell lines.
    Cancer Cell 40:835-849.e8(2022)

    Cross-references
    Cell line collections (Providers)ECACC; 86022703
    Cell line databases/resourcesCLO; CLO_0007818
    CLDB; cl3513
    cancercelllines; CVCL_2614
    Cell_Model_Passport; SIDM00504
    Cosmic-CLP; 908145
    DepMap; ACH-001126
    LINCS_LDP; LCL-1397
    Biological sample resourcesBioSample; SAMN03470987
    BioSample; SAMN10988296
    CRISP screens repositoriesBioGRID_ORCS_Cell_line; 945
    Chemistry resourcesChEMBL-Cells; CHEMBL3308137
    ChEMBL-Targets; CHEMBL1075508
    GDSC; 90815
    PharmacoDB; MOGGUVW_949_2019
    PubChem_Cell_line; CVCL_2614
    Encyclopedic resourcesWikidata; Q54906313
    Gene expression databasesArrayExpress; E-MTAB-783
    ArrayExpress; E-MTAB-3610
    GEO; GSM827433
    GEO; GSM1374687
    GEO; GSM1670123
    Polymorphism and mutation databasesCosmic; 908145
    Cosmic; 2367539
    IARC_TP53; 21510
    Progenetix; CVCL_2614
    Proteomic databasesPRIDE; PXD030304
    Sequence databasesEGA; EGAS00001000978
    Entry history
    Entry creation04-Apr-2012
    Last entry update30-Jan-2024
    Version number34

    更多>>相关产品

    总部地址:北京市怀柔区渤海镇怀沙路536号

    关注杏鑫
    在线咨询
    在线客服
    电话咨询
    微信客服
    返回顶部
    杏鑫娱乐专业提供:杏鑫娱乐🧘🏻‍♀️、杏鑫👱‍♀️、杏鑫平台等服务,提供最新官网平台、地址、注册、登陆、登录、入口、全站、网站、网页、网址、娱乐、手机版、app、下载、欧洲杯、欧冠、nba、世界杯、英超等,界面美观优质完美,安全稳定,服务一流㊙️,杏鑫娱乐欢迎您。