• Mahlavu人肝癌细胞(STR鉴定正确)

    价 格:¥2400

    期 货🫏:现货(冻存管发2支)

    保藏中心👩🏻‍💼:BTCC

    资源编号:BTCC-1460

    产地:中国

    套 餐:

    T25/复苏细胞 无血清冻存液 专用完全培养基500ml 南美特级胎牛血清500ml

    详细资料说明书下载质检报告(COA)

    Cell line nameMahlavu
    SynonymsMAHLAVU
    AccessionBTCC-1460
    Resource Identification InitiativeTo cite this cell line use: Mahlavu (RRID:BTCC-1460)
    CommentsPart of: Liver Cancer Model Repository (LIMORE).
    Population: African.
    Doubling time: 22.5 hours (CelloPub=CLPUB00076); 52.01 hours (PubMed=31378681).
    Omics: Genomics; Whole exome sequencing.
    Omics: Genomics; Whole genome sequencing.
    Omics: Proteomics; Expression; Reverse-phase protein array.
    Omics: Transcriptomics; miRNA profiling; Microarray.
    Omics: Transcriptomics; RNAseq.
    Misspelling: Malhavu; Note=Occasionally.
    Derived from site: In situ; Liver; UBERON=UBERON_0002107.
    Sequence variations
    DiseaseHepatocellular carcinoma (NCIt: C3099)
    Hepatocellular carcinoma (ORDO: Orphanet_88673)
    Species of originHomo sapiens (Human) (NCBI Taxonomy: 9606)
    Sex of cellFemale
    Age at samplingAge unspecified
    CategoryCancer cell line
    STR profileSource(s): CLS=300473; PubMed=31378681

    Markers:
    AmelogeninX
    CSF1PO7,11
    D2S133819,22
    D3S135817
    D5S81812
    D6S104312
    D7S82010,11
    D8S117911,14
    D12S39118
    D13S31712,13
    D16S53911
    D18S5115
    D19S43311,14
    D21S1131.2,32.2
    FGA28
    Penta D9,11
    Penta E8,11
    TH017
    TPOX8,10
    vWA15

    Run an STR similarity search on this cell line
    Web pagesInfo; LCCL; -; https://lccl.zucmanlab.com/hcc/cellLines/Mahlavu
    Provider; BRICS; BRICS0078; http://www.brics.ac.cn/cell/template/cell/cell_detail.html?id=3892
    Publications

    CLPUB00076
    Prozesky O.W., Brits C.J., Grabow W.O.K.
    In vitro culture of cell lines from Australia antigen positive and negative hepatoma patients.
    (In book chapter) Liver; Saunders S.J., Terblanche J. (eds.); pp.358-360; Pitman Medical Books; London; United Kingdom (1973)

    CLPUB00575
    Prozesky O.W., Lecatsas G.
    Scanning electron microscopy of a human hepatoma cell line.
    S. Afr. Med. J. 49:1061-1062(1975)

    PubMed=179808; DOI=10.1111/j.1432-1033.1976.tb10294.x
    Grimm J.
    The influence of insulin on various enzyme activities in human and rat hepatoma cells.
    Eur. J. Biochem. 64:249-253(1976)

    PubMed=6268737; DOI=10.1099/0022-1317-53-1-105
    Oefinger P.E., Bronson D.L., Dreesman G.R.
    Induction of hepatitis B surface antigen in human hepatoma-derived cell lines.
    J. Gen. Virol. 53:105-113(1981)

    PubMed=6275024; DOI=10.1099/0022-1317-57-1-95
    Koshy R., Maupas P., Muller R., Hofschneider P.H.
    Detection of hepatitis B virus-specific DNA in the genomes of human hepatocellular carcinoma and liver cirrhosis tissues.
    J. Gen. Virol. 57:95-102(1981)

    DOI=10.1007/978-4-431-68349-0_4
    Alexander J.J.
    Human hepatoma cell lines.
    (In book chapter) Neoplasms of the liver; Okuda K., Ishak K.G. (eds.); pp.47-56; Springer; Tokyo; Japan (1987)

    PubMed=2439335; DOI=10.1111/j.1432-1033.1987.tb11497.x
    Vincent C., Marceau M., Blangarin P., Bouic P., Madjar J.-J., Revillard J.-P.
    Purification of alpha 1-microglobulin produced by human hepatoma cell lines. Biochemical characterization and comparison with alpha 1-microglobulin synthesized by human hepatocytes.
    Eur. J. Biochem. 165:699-704(1987)

    PubMed=8224613; DOI=10.1096/fasebj.7.14.8224613
    Puisieux A., Galvin K., Troalen F., Bressac B., Marcais C., Galun E., Ponchel F., Yakicier C., Ji J.-W., Ozturk M.
    Retinoblastoma and p53 tumor suppressor genes in human hepatoma cell lines.
    FASEB J. 7:1407-1413(1993)

    PubMed=8050184; DOI=10.1111/j.1365-2249.1994.tb06089.x; PMCID=PMC1534706
    Wadee A.A., Paterson A., Coplan K.A., Reddy S.G.
    HLA expression in hepatocellular carcinoma cell lines.
    Clin. Exp. Immunol. 97:328-333(1994)

    PubMed=23887712; DOI=10.1038/ncomms3218; PMCID=PMC3731665
    Nault J.-C., Mallet M., Pilati C., Calderaro J., Bioulac-Sage P., Laurent C., Laurent A., Cherqui D., Balabaud C., Zucman-Rossi J.
    High frequency of telomerase reverse-transcriptase promoter somatic mutations in hepatocellular carcinoma and preneoplastic lesions.
    Nat. Commun. 4:2218.1-2218.7(2013)

    PubMed=25574106; DOI=10.3748/wjg.v21.i1.311; PMCID=PMC4284350
    Cevik D., Yildiz G., Ozturk M.
    Common telomerase reverse transcriptase promoter mutations in hepatocellular carcinomas from different geographical locations.
    World J. Gastroenterol. 21:311-317(2015)

    PubMed=31063779; DOI=10.1053/j.gastro.2019.05.001
    Caruso S., Calatayud A.-L., Pilet J., La Bella T., Rekik S., Imbeaud S., Letouze E., Meunier L., Bayard Q., Rohr-Udilova N., Peneau C., Grasl-Kraupp B., de Koning L., Ouine B., Bioulac-Sage P., Couchy G., Calderaro J., Nault J.-C., Zucman-Rossi J., Rebouissou S.
    Analysis of liver cancer cell lines identifies agents with likely efficacy against hepatocellular carcinoma and markers of response.
    Gastroenterology 157:760-776(2019)

    PubMed=31378681; DOI=10.1016/j.ccell.2019.07.001; PMCID=PMC7505724
    Qiu Z.-X., Li H., Zhang Z.-T., Zhu Z.-F., He S., Wang X.-J., Wang P.-C., Qin J.-J., Zhuang L.-P., Wang W., Xie F.-B., Gu Y., Zou K.-K., Li C., Li C., Wang C.-H., Cen J., Chen X.-T., Shu Y.-J., Zhang Z., Sun L.-L., Min L.-H., Fu Y., Huang X.-W., Lv H., Zhou H., Ji Y., Zhang Z.-G., Meng Z.-Q., Shi X.-L., Zhang H.-B., Li Y.-X., Hui L.-J.
    A pharmacogenomic landscape in human liver cancers.
    Cancer Cell 36:179-193.e11(2019)

    Cross-references
    Cell line collections (Providers)CLS; 300473
    Cell line databases/resourcesMCCL; MCC:0000299
    cancercelllines; CVCL_0405
    LIMORE; Mahlavu
    Anatomy/cell type resourcesBTO; BTO_0004471
    Chemistry resourcesChEMBL-Cells; CHEMBL4295417
    ChEMBL-Targets; CHEMBL4296473
    PubChem_Cell_line; CVCL_0405
    Encyclopedic resourcesWikidata; Q54903975
    Experimental variables resourcesEFO; EFO_0022710
    Gene expression databasesGEO; GSM2551578
    Polymorphism and mutation databasesCosmic; 873398
    Cosmic; 948064
    Cosmic; 979727
    Cosmic; 1019317
    Cosmic; 2162534
    Cosmic; 2321039
    IARC_TP53; 2183

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