SAS人舌头鳞状肿瘤细胞(STR鉴定正确)

    价 格:¥3000

    期 货🧙🏼:现货(冻存管发2支)

    保藏中心:BTCC

    资源编号✶:BTCC-1345

    产地:中国

    套 餐:

    T25/复苏细胞 无血清冻存液 专用完全培养基500ml 南美特级胎牛血清500ml

    详细资料说明书下载质检报告(COA)

    Cell line nameSW982
    SynonymsSW-982; SW 982
    AccessionBTCC-1345
    Resource Identification InitiativeTo cite this cell line use: SW982 (BTCC-1345)
    CommentsPart of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
    Part of: COSMIC cell lines project.
    Part of: MD Anderson Cell Lines Project.
    From: Scott and White Clinic; Temple; USA.
    Population: Caucasian.
    Microsatellite instability: Stable (MSS) (Sanger).
    Omics: Deep exome analysis.
    Omics: Deep quantitative proteome analysis.
    Omics: DNA methylation analysis.
    Omics: Protein expression by reverse-phase protein arrays.
    Omics: SNP array analysis.
    Omics: Transcriptome analysis by microarray.
    Omics: Transcriptome analysis by RNAseq.
    Caution: Stated to originate from a patient with a biphasic synovial sarcoma, however does not contain the SST-SSX1/SSX2 translocation which is typical of synovial sarcoma.
    Derived from site: In situ; Synovium; UBERON=UBERON_0007616.
    Sequence variations
    • Gene deletion; HGNC; 7208; MPDZ; Zygosity=Homozygous (PubMed=20215515).
    • Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (Cosmic-CLP; DepMap).
    HLA typingSource: PubMed=26589293
    Class I
    HLA-AA*02:01,02:01
    HLA-BB*07:02,49:01
    HLA-CC*07:01,07:01
    Genome ancestrySource: PubMed=30894373

    Origin% genome


    African0
    Native American0.11
    East Asian, North0
    East Asian, South0
    South Asian2.82
    European, North67.54
    European, South29.52
    DiseaseBiphasic synovial sarcoma (NCIt: C4279)
    Synovial sarcoma (ORDO: Orphanet_3273)
    Species of originHomo sapiens (Human) (NCBI Taxonomy: 9606)
    Sex of cellFemale
    Age at sampling25Y
    CategoryCancer cell line
    STR profileSource(s): ATCC; CLS; Cosmic-CLP; PubMed=25877200

    Markers:
    AmelogeninX
    CSF1PO11,12
    D3S135815
    D5S81811,13 (ATCC; CLS; Cosmic-CLP)
    13 (PubMed=25877200)
    D7S8209,11
    D8S117911,14
    D13S3178,12,13 (CLS)
    12,13 (ATCC; Cosmic-CLP; PubMed=25877200)
    D16S53911,12
    D18S5116,18
    D21S1128,30
    FGA21,24
    Penta D10,13
    Penta E13,15
    TH019.3
    TPOX9,11
    vWA19,20

    Run an STR similarity search on this cell line
    Web pageshttps://tcpaportal.org/mclp/
    Publications

    PubMed=833871; DOI=10.1093/jnci/58.2.209
    Fogh J., Wright W.C., Loveless J.D.
    Absence of HeLa cell contamination in 169 cell lines derived from human tumors.
    J. Natl. Cancer Inst. 58:209-214(1977)

    PubMed=3518877; DOI=10.3109/07357908609038260
    Fogh J.
    Human tumor lines for cancer research.
    Cancer Invest. 4:157-184(1986)

    DOI=10.1007/978-94-011-3550-4_4
    Hay R.J.
    Development, availability and characterization of ATCC human and animal cell lines.
    (In) Animal cell culture and production of biologicals; Sasaki R., Ikura K. (eds.); pp.27-39; Springer; Dordrecht (1991)

    PubMed=15038780; DOI=10.1290/1543-706X(2003)039<0337:pcoahs>2.0.CO;2
    Yamazaki T., Yokoyama T., Akatsu H., Tukiyama T., Tokiwa T.
    Phenotypic characterization of a human synovial sarcoma cell line, SW982, and its response to dexamethasone.
    In Vitro Cell. Dev. Biol. Anim. 39:337-339(2003)

    PubMed=20164919; DOI=10.1038/nature08768
    Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B.-Y., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.
    Signatures of mutation and selection in the cancer genome.
    Nature 463:893-898(2010)

    PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
    Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
    A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
    Cancer Res. 70:2158-2164(2010)

    PubMed=25485619; DOI=10.1038/nbt.3080
    Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z.-S., Liu H.-B., Degenhardt J., Mayba O., Gnad F., Liu J.-F., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M.-M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.-M.
    A comprehensive transcriptional portrait of human cancer cell lines.
    Nat. Biotechnol. 33:306-312(2015)

    PubMed=26351324; DOI=10.1158/1535-7163.MCT-15-0074
    Teicher B.A., Polley E.C., Kunkel M., Evans D., Silvers T.E., Delosh R.M., Laudeman J., Ogle C., Reinhart R., Selby M., Connelly J., Harris E., Monks A., Morris J.
    Sarcoma cell line screen of oncology drugs and investigational agents identifies patterns associated with gene and microRNA expression.
    Mol. Cancer Ther. 14:2452-2462(2015)

    PubMed=26589293; DOI=10.1186/s13073-015-0240-5
    Scholtalbers J., Boegel S., Bukur T., Byl M., Goerges S., Sorn P., Loewer M., Sahin U., Castle J.C.
    TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
    Genome Med. 7:118.1-118.7(2015)

    PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
    Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X.-M., Egan R.K., Liu Q.-S., Mironenko T., Mitropoulos X., Richardson L., Wang J.-H., Zhang T.-H., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
    A landscape of pharmacogenomic interactions in cancer.
    Cell 166:740-754(2016)

    PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
    Li J., Zhao W., Akbani R., Liu W.-B., Ju Z.-L., Ling S.-Y., Vellano C.P., Roebuck P., Yu Q.-H., Eterovic A.K., Byers L.A., Davies M.A., Deng W.-L., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y.-L., Mills G.B., Liang H.
    Characterization of human cancer cell lines by reverse-phase protein arrays.
    Cancer Cell 31:225-239(2017)

    PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
    Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
    An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
    Cancer Res. 79:1263-1273(2019)

    PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010
    Goncalves E., Poulos R.C., Cai Z.-X., Barthorpe S., Manda S.S., Lucas N., Beck A., Bucio-Noble D., Dausmann M., Hall C., Hecker M., Koh J., Lightfoot H., Mahboob S., Mali I., Morris J., Richardson L., Seneviratne A.J., Shepherd R., Sykes E., Thomas F., Valentini S., Williams S.G., Wu Y.-X., Xavier D., MacKenzie K.L., Hains P.G., Tully B., Robinson P.J., Zhong Q., Garnett M.J., Reddel R.R.
    Pan-cancer proteomic map of 949 human cell lines.
    Cancer Cell 40:835-849.e8(2022)

    Cross-references
    Cell line databases/resourcesCLO; CLO_0009206
    CCRID; 3101HUMTCHu209
    Cell_Model_Passport; SIDM01161
    Cosmic-CLP; 909759
    DepMap; ACH-001274
    IGRhCellID; SW982
    LINCS_LDP; LCL-1880
    Anatomy/cell type resourcesBTO; BTO:0006386
    Biological sample resourcesBioSample; SAMN03471376
    BioSample; SAMN03472764
    Cell line collections (Providers)ATCC; HTB-93
    BCRC; 60535
    CLS; 300404
    Chemistry resourcesChEMBL-Cells; CHEMBL3308534
    ChEMBL-Targets; CHEMBL2366238
    GDSC; 909759
    PharmacoDB; SW982_1552_2019
    PubChem_Cell_line; CVCL_1734
    Encyclopedic resourcesWikidata; Q54971230
    Experimental variables resourcesEFO; EFO_0002378

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