• MIN6小鼠胰岛β细胞

    价 格🥎:¥2400

    期 货🐺:现货(冻存管发2支)

    保藏中心🏃:BTCC

    资源编号⛺️:BTCC-2008

    产地🧜🏼‍♂️:中国

    套 餐:

    T25/复苏细胞 无血清冻存液 专用完全培养基500ml 南美特级胎牛血清500ml

    详细资料说明书下载质检报告(COA)

    Cell line nameMIN6
    SynonymsMin6; MIN-6; Mouse INsulinoma 6
    AccessionBBTCC-2008
    Resource Identification InitiativeTo cite this cell line use: MIN6 (BTCC-2008)
    CommentsTransformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
    Omics: Cell surface proteome.
    Omics: Endoplasmic reticulum proteome analysis.
    Derived from site: In situ; Pancreas, islets of Langerhans; UBERON=UBERON_0000006.
    Cell type: Pancreatic beta cell; CL=CL_0000169.
    DiseaseMouse insulinoma (NCIt: C34053)
    Species of originMus musculus (Mouse) (NCBI Taxonomy: 10090)
    Breed/subspecies: C57BL/6 IT6 transgenic.
    HierarchyChildren:



    CVCL_A7QH (MIN6 rho0)CVCL_A8QH (MIN6-cl4)CVCL_4372 (MIN6-m14)
    CVCL_4371 (MIN6-m9)CVCL_D686 (MIN6N8)
    Sex of cellSex unspecified
    Age at sampling13W
    CategoryTransformed cell line
    Web pageshttps://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/m/cell-lines-detail-93.html
    Publications

    PubMed=2163307; DOI=10.1210/endo-127-1-126
    Miyazaki J.-I., Araki K., Yamato E., Ikegami H., Asano T., Shibasaki Y., Oka Y., Yamamura K.-I.
    Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms.
    Endocrinology 127:126-132(1990)

    PubMed=8697299
    Poitout V., Olson L.K., Robertson R.P.
    Insulin-secreting cell lines: classification, characteristics and potential applications.
    Diabetes Metab. 22:7-14(1996)

    PubMed=8824267; DOI=10.1074/jbc.271.42.26194
    Soejima A., Inoue K., Takai D., Kaneko M., Ishihara H., Oka Y., Hayashi J.-I.
    Mitochondrial DNA is required for regulation of glucose-stimulated insulin secretion in a mouse pancreatic beta cell line, MIN6.
    J. Biol. Chem. 271:26194-26199(1996)

    PubMed=18845907; DOI=10.1507/endocrj.K08E-172
    Nakashima K., Kanda Y., Hirokawa Y., Kawasaki F., Matsuki M., Kaku K.
    MIN6 is not a pure beta cell line but a mixed cell line with other pancreatic endocrine hormones.
    Endocr. J. 56:45-53(2009)

    PubMed=22538498; DOI=10.1159/000338793
    Grozinsky-Glasberg S., Shimon I., Rubinfeld H.
    The role of cell lines in the study of neuroendocrine tumors.
    Neuroendocrinology 96:173-187(2012)

    PubMed=22808281; DOI=10.1371/journal.pone.0040868
    Cheng K., Delghingaro-Augusto V., Nolan C.J., Turner N., Hallahan N., Andrikopoulos S., Gunton J.E.
    High passage MIN6 cells have impaired insulin secretion with impaired glucose and lipid oxidation.
    PLoS ONE 7:E40868-E40868(2012)

    PubMed=23560115; DOI=10.1371/journal.pone.0061211
    Yamato E., Tashiro F., Miyazaki J.-I.
    Microarray analysis of novel candidate genes responsible for glucose-stimulated insulin secretion in mouse pancreatic beta cell line MIN6.
    PLoS ONE 8:E61211-E61211(2013)

    PubMed=25546123; DOI=10.1002/pmic.201400345
    Lee J.-S., Wu Y.-N., Schnepp P., Fang J.-Y., Zhang X.-B., Karnovsky A., Woods J., Stemmer P.M., Liu M., Zhang K.-Z., Chen X.-Q.
    Proteomics analysis of rough endoplasmic reticulum in pancreatic beta cells.
    Proteomics 15:1508-1511(2015)

    PubMed=25894527; DOI=10.1371/journal.pone.0121314
    Bausch-Fluck D., Hofmann A., Bock T., Frei A.P., Cerciello F., Jacobs A., Moest H., Omasits U., Gundry R.L., Yoon C., Schiess R., Schmidt A., Mirkowska P., Hartlova A.S., Van Eyk J.E., Bourquin J.-P., Aebersold R., Boheler K.R., Zandstra P.W., Wollscheid B.
    A mass spectrometric-derived cell surface protein atlas.
    PLoS ONE 10:E0121314-E0121314(2015)

    Cross-references
    Cell line databases/resourcesMCCL; MCC:0000326
    Lonza; 163
    Anatomy/cell type resourcesBTO; BTO:0002284
    Cell line collections (Providers)AddexBio; C0018008/403
    BCRJ; 0293
    IBRC; C10524
    Chemistry resourcesChEMBL-Cells; CHEMBL4483177
    ChEMBL-Targets; CHEMBL4483258
    PubChem_Cell_line; CVCL_0431
    Encyclopedic resourcesWikidata; Q12513178
    Experimental variables resourcesEFO; EFO_0002829
    Proteomic databasesPRIDE; PXD000589
    PRIDE; PXD001081

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